Systemic contact dermatitis from propylene glycol. Systematic and systemic both come from system. Learn more. systemic, adj. Systematic is the more common word; it most often describes something that is done according to a system or method. Definition of systemic adjective in Oxford Advanced Learner's Dictionary. & n. Systematic and systemic both come from system. SYSTEMIC definition: of or relating to a system, especially when affecting the entirety of a thing. pertaining to or affecting a particular body system. It can be used in various contexts like biology, medicine, sociology, or politics, indicating a widespread issue or condition impacting an entire organism, organization, or society, rather than isolated parts. Pathology [Physiol. Biology relating to, affecting, or circulating through the entire body: systemic disease. Meaning, pronunciation, picture, example sentences, grammar, usage notes, synonyms and more. Systemic definition: Of or relating to systems or a system. . ] pertaining to or affecting the body as a whole. Systemic describes what relates to or affects an entire system, be that system physical, organizational, or societal. Jan 20, 2026 · Adjective systemic (not comparable) Embedded within and spread throughout and affecting a whole system, group, body, economy, market, or society. meanings, etymology, pronunciation and more in the Oxford English Dictionary Systemic refers to something that is pervasive and affects an entire system, often used in contexts like medicine, biology, or organizational changes. , Pathol. Pathology of or pertaining to a system. In medicine, a systemic condition, treatment, or reaction is one that travels through your bloodstream and reaches tissues and organs throughout your body, as opposed to staying in one localized area. SYSTEMIC definition: 1. See examples of systemic used in a sentence. Systemic refers to something that is prevalent throughout or affecting the whole system or body. A systemic drug, disease, or poison reaches and has an effect on the whole of a body or a plant…. “Systemic” means affecting the entire body rather than a single spot. sqly utff jylpm edhes euirlu jaucx gms tzjg mjfikidei jvoovu